Author: Akul Mehta
Abstract:
Ever since the discovery of alpha-fetoprotein
(AFP) by Bergstrand and Czar in the year
1956, extensive research has been carried
out on this molecular wonder of nature to
elucidate its functions, its role and its
widespread presence. This fetal component
which was not commonly observed in adults was first
found as a post albumin migrating protein in
fetal serum. Its functions are varied from
development of the fetus, where it acts as a
major transport protein, to a serum marker in
cancer, and its uses in the detection of
congenital defects. The following discussion
takes a closer look at the molecule with greater insight into its structure, its role
played in the human body, its biochemical
functions, and the potential uses of the AFP
molecule.